Screening of Methylation Signature and Gene Functions Associated With the Subtypes of Isocitrate Dehydrogenase-Mutation Gliomas

Isocitrate dehydrogenase (IDH) is an oncogene, and the expression of a mutated IDH promotes cell proliferation and inhibits cell differentiation. IDH exists in three different isoforms, whose mutation can cause many solid tumors, especially gliomas in adults. No effective method for classifying glio...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Pan, XiaoYong, Zeng, Tao, Yuan, Fei, Zhang, Yu-Hang, Chen, Lei, Zhu, LiuCun, Wan, SiBao, Huang, Tao, Cai, Yu-Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871504/
https://ncbi.nlm.nih.gov/pubmed/31803734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00339
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