Screening of Methylation Signature and Gene Functions Associated With the Subtypes of Isocitrate Dehydrogenase-Mutation Gliomas

Isocitrate dehydrogenase (IDH) is an oncogene, and the expression of a mutated IDH promotes cell proliferation and inhibits cell differentiation. IDH exists in three different isoforms, whose mutation can cause many solid tumors, especially gliomas in adults. No effective method for classifying glio...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Pan, XiaoYong, Zeng, Tao, Yuan, Fei, Zhang, Yu-Hang, Chen, Lei, Zhu, LiuCun, Wan, SiBao, Huang, Tao, Cai, Yu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871504/
https://ncbi.nlm.nih.gov/pubmed/31803734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00339
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