Screening of Methylation Signature and Gene Functions Associated With the Subtypes of Isocitrate Dehydrogenase-Mutation Gliomas

Isocitrate dehydrogenase (IDH) is an oncogene, and the expression of a mutated IDH promotes cell proliferation and inhibits cell differentiation. IDH exists in three different isoforms, whose mutation can cause many solid tumors, especially gliomas in adults. No effective method for classifying glio...

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Bibliografiske detaljer
Udgivet i:Front Bioeng Biotechnol
Main Authors: Pan, XiaoYong, Zeng, Tao, Yuan, Fei, Zhang, Yu-Hang, Chen, Lei, Zhu, LiuCun, Wan, SiBao, Huang, Tao, Cai, Yu-Dong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Bioengineering and Biotechnology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871504/
https://ncbi.nlm.nih.gov/pubmed/31803734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00339
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