Screening of Methylation Signature and Gene Functions Associated With the Subtypes of Isocitrate Dehydrogenase-Mutation Gliomas

Isocitrate dehydrogenase (IDH) is an oncogene, and the expression of a mutated IDH promotes cell proliferation and inhibits cell differentiation. IDH exists in three different isoforms, whose mutation can cause many solid tumors, especially gliomas in adults. No effective method for classifying glio...

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Dades bibliogràfiques
Publicat a:Front Bioeng Biotechnol
Autors principals: Pan, XiaoYong, Zeng, Tao, Yuan, Fei, Zhang, Yu-Hang, Chen, Lei, Zhu, LiuCun, Wan, SiBao, Huang, Tao, Cai, Yu-Dong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Bioengineering and Biotechnology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871504/
https://ncbi.nlm.nih.gov/pubmed/31803734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00339
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