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Screening of Methylation Signature and Gene Functions Associated With the Subtypes of Isocitrate Dehydrogenase-Mutation Gliomas

Isocitrate dehydrogenase (IDH) is an oncogene, and the expression of a mutated IDH promotes cell proliferation and inhibits cell differentiation. IDH exists in three different isoforms, whose mutation can cause many solid tumors, especially gliomas in adults. No effective method for classifying glio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Bioeng Biotechnol
Prif Awduron: Pan, XiaoYong, Zeng, Tao, Yuan, Fei, Zhang, Yu-Hang, Chen, Lei, Zhu, LiuCun, Wan, SiBao, Huang, Tao, Cai, Yu-Dong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871504/
https://ncbi.nlm.nih.gov/pubmed/31803734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00339
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