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The role of protein conformational fluctuations in allostery, function, and evolution
It is now well-known that proteins exist at equilibrium as ensembles of conformational states rather than as unique static structures. Here we review from an ensemble perspective important biological effects of such spontaneous fluctuations on protein allostery, function, and evolution. However, rat...
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| Udgivet i: | Biophys Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6583903/ https://ncbi.nlm.nih.gov/pubmed/21684672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2011.05.020 |
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