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NOTCH3 and CADASIL syndrome: a genetic and structural overview

CADASIL syndrome is a rare disease that belongs to a group of disorders called leukodystrophies. It is well established that NOTCH3 gene on chromosome 19 is primarily responsible for the development of the CADASIL syndrome. Herein, an attempt is made to shed light on the actual molecular mechanism u...

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Detalles Bibliográficos
Publicado en:EMBnet J
Main Authors: Papakonstantinou, Eleni, Bacopoulou, Flora, Brouzas, Dimitrios, Megalooikonomou, Vasileios, D’Elia, Domenica, Bongcam-Rudloff, Erik, Vlachakis, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583802/
https://ncbi.nlm.nih.gov/pubmed/31218211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14806/ej.24.0.921
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