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NOTCH3 and CADASIL syndrome: a genetic and structural overview

CADASIL syndrome is a rare disease that belongs to a group of disorders called leukodystrophies. It is well established that NOTCH3 gene on chromosome 19 is primarily responsible for the development of the CADASIL syndrome. Herein, an attempt is made to shed light on the actual molecular mechanism u...

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Publicado en:EMBnet J
Autores principales: Papakonstantinou, Eleni, Bacopoulou, Flora, Brouzas, Dimitrios, Megalooikonomou, Vasileios, D’Elia, Domenica, Bongcam-Rudloff, Erik, Vlachakis, Dimitrios
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583802/
https://ncbi.nlm.nih.gov/pubmed/31218211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14806/ej.24.0.921
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