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NOTCH3 and CADASIL syndrome: a genetic and structural overview

CADASIL syndrome is a rare disease that belongs to a group of disorders called leukodystrophies. It is well established that NOTCH3 gene on chromosome 19 is primarily responsible for the development of the CADASIL syndrome. Herein, an attempt is made to shed light on the actual molecular mechanism u...

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Podrobná bibliografie
Vydáno v:EMBnet J
Hlavní autoři: Papakonstantinou, Eleni, Bacopoulou, Flora, Brouzas, Dimitrios, Megalooikonomou, Vasileios, D’Elia, Domenica, Bongcam-Rudloff, Erik, Vlachakis, Dimitrios
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583802/
https://ncbi.nlm.nih.gov/pubmed/31218211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14806/ej.24.0.921
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