Lanean...

10β,17α-Dihydroxyestra-1,4-dien-3-one: A bioprecursor prodrug preferentially producing 17α-estradiol in the brain for targeted neurotherapy

Uterotrophic effect of 17α-estradiol, the C17 epimer of the main human estrogen 17β-estradiol, was shown to manifest in animal models at doses lower than those necessary for central outcome raising concerns about its potential to treat maladies of the central nervous system. We introduce here 10β,17...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ACS Chem Neurosci
Egile Nagusiak: Prokai-Tatrai, Katalin, Nguyen, Vien, Prokai, Laszlo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582959/
https://ncbi.nlm.nih.gov/pubmed/29843514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00184
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!