Scn2a Haploinsufficiency in Mice Suppresses Hippocampal Neuronal Excitability, Excitatory Synaptic Drive, and Long-Term Potentiation, and Spatial Learning and Memory

Nav1.2, a voltage-gated sodium channel subunit encoded by the Scn2a gene, has been implicated in various brain disorders, including epilepsy, autism spectrum disorder, intellectual disability, and schizophrenia. Nav1.2 is known to regulate the generation of action potentials in the axon initial segm...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Mol Neurosci
Egile Nagusiak: Shin, Wangyong, Kweon, Hanseul, Kang, Ryeonghwa, Kim, Doyoun, Kim, Kyungdeok, Kang, Muwon, Kim, Seo Yeong, Hwang, Sun Nam, Kim, Jin Yong, Yang, Esther, Kim, Hyun, Kim, Eunjoon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Neuroscience
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582764/
https://ncbi.nlm.nih.gov/pubmed/31249508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00145
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