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An improved method for isolation of mitochondria from cell lines that enables reconstitution of calcium-dependent processes

Optimum cytosolic calcium concentrations support balanced mitochondrial respiration. However, the concentration of cytosolic Ca(2+) varies among cell types and excess cytosolic Ca(2+) can cause mitochondrial dysfunction, particularly when the mitochondria are isolated from cell lines. We optimized a...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Ishii, Masaaki, Beeson, Gyda, Beeson, Craig, Rohrer, Bärbel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582631/
https://ncbi.nlm.nih.gov/pubmed/31022379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2019.04.012
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