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Mitochondrial C3a Receptor Activation in Oxidatively Stressed Epithelial Cells Reduces Mitochondrial Respiration and Metabolism

Complement component 3 fragment C3a is an anaphylatoxin involved in promoting cellular responses important in immune response and host defense. Its receptor (C3a receptor, C3aR) is distributed on the plasma membrane; however, lysosomal localization in immune cells has been reported. Oxidative stress...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ishii, Masaaki, Beeson, Gyda, Beeson, Craig, Rohrer, Bärbel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973370/
https://ncbi.nlm.nih.gov/pubmed/33746964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.628062
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