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Acetate and Butyrate Improve β-cell Metabolism and Mitochondrial Respiration under Oxidative Stress

Islet dysfunction mediated by oxidative and mitochondrial stress contributes to the development of type 1 and 2 diabetes. Acetate and butyrate, produced by gut microbiota via fermentation, have been shown to protect against oxidative and mitochondrial stress in many cell types, but their effect on p...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hu, Shuxian, Kuwabara, Rei, de Haan, Bart J., Smink, Alexandra M., de Vos, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073211/
https://ncbi.nlm.nih.gov/pubmed/32102422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041542
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