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Mitochondrial respiration and ROS emission during β-oxidation in the heart: An experimental-computational study

Lipids are main fuels for cellular energy and mitochondria their major oxidation site. Yet unknown is to what extent the fuel role of lipids is influenced by their uncoupling effects, and how this affects mitochondrial energetics, redox balance and the emission of reactive oxygen species (ROS). Empl...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Cortassa, Sonia, Sollott, Steven J., Aon, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482492/
https://ncbi.nlm.nih.gov/pubmed/28598967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005588
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