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Mitochondrial respiration and ROS emission during β-oxidation in the heart: An experimental-computational study

Lipids are main fuels for cellular energy and mitochondria their major oxidation site. Yet unknown is to what extent the fuel role of lipids is influenced by their uncoupling effects, and how this affects mitochondrial energetics, redox balance and the emission of reactive oxygen species (ROS). Empl...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Cortassa, Sonia, Sollott, Steven J., Aon, Miguel A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482492/
https://ncbi.nlm.nih.gov/pubmed/28598967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005588
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