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Continuous‐flow Synthesis of Aryl Aldehydes by Pd‐catalyzed Formylation of Aryl Bromides Using Carbon Monoxide and Hydrogen

A continuous‐flow protocol utilizing syngas (CO and H(2)) was developed for the palladium‐catalyzed reductive carbonylation of (hetero)aryl bromides to their corresponding (hetero)aryl aldehydes. The optimization of temperature, pressure, catalyst and ligand loading, and residence time resulted in p...

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Detalhes bibliográficos
Publicado no:ChemSusChem
Main Authors: Hone, Christopher A., Lopatka, Pavol, Munday, Rachel, O'Kearney‐McMullan, Anne, Kappe, C. Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582436/
https://ncbi.nlm.nih.gov/pubmed/30300970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cssc.201802261
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