Continuous‐Flow Pd‐Catalyzed Carbonylation of Aryl Chlorides with Carbon Monoxide at Elevated Temperature and Pressure

The development of a continuous‐flow protocol for a palladium‐catalyzed methoxycarbonylation of (hetero)aryl chlorides using carbon monoxide gas and methanol is described. (Hetero)aryl chlorides are the least expensive of the aryl halides, but are underutilized in carbonylation reactions due to thei...

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Bibliographic Details
Published in:ChemCatChem
Main Authors: Mata, Alejandro, Hone, Christopher A., Gutmann, Bernhard, Moens, Luc, Kappe, C. Oliver
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813631/
https://ncbi.nlm.nih.gov/pubmed/31681449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cctc.201801974
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