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An Efficient System For the Pd-Catalyzed Cross-Coupling of Amides and Aryl Chlorides

A catalyst based on a new biarylphosphine ligand (3) for the Pd-catalyzed cross-coupling reactions of amides and aryl chlorides is described. This system shows the highest turnover frequencies reported to date for these reactions, especially for aryl chloride substrates bearing an ortho substituent....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fors, Brett P., Dooleweerdt, Karin, Zeng, Qingle, Buchwald, Stephen L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927134/
https://ncbi.nlm.nih.gov/pubmed/20740063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2009.04.096
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