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PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription
Regulation of RNA polymerase II (RNAPII)-mediated transcription controls cellular phenotypes such as cancer. Phosphatase and tensin homologue deleted on chromosome ten (PTEN), one of the most commonly altered tumor suppressors in cancer, affects transcription via its role in antagonizing the PI3K/AK...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6582409/ https://ncbi.nlm.nih.gov/pubmed/31169889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz272 |
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