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PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription

Regulation of RNA polymerase II (RNAPII)-mediated transcription controls cellular phenotypes such as cancer. Phosphatase and tensin homologue deleted on chromosome ten (PTEN), one of the most commonly altered tumor suppressors in cancer, affects transcription via its role in antagonizing the PI3K/AK...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Steinbach, Nicole, Hasson, Dan, Mathur, Deepti, Stratikopoulos, Elias E, Sachidanandam, Ravi, Bernstein, Emily, Parsons, Ramon E
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582409/
https://ncbi.nlm.nih.gov/pubmed/31169889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz272
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