PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription

Regulation of RNA polymerase II (RNAPII)-mediated transcription controls cellular phenotypes such as cancer. Phosphatase and tensin homologue deleted on chromosome ten (PTEN), one of the most commonly altered tumor suppressors in cancer, affects transcription via its role in antagonizing the PI3K/AK...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Steinbach, Nicole, Hasson, Dan, Mathur, Deepti, Stratikopoulos, Elias E, Sachidanandam, Ravi, Bernstein, Emily, Parsons, Ramon E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Gene regulation, Chromatin and Epigenetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582409/
https://ncbi.nlm.nih.gov/pubmed/31169889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz272
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