PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription

Regulation of RNA polymerase II (RNAPII)-mediated transcription controls cellular phenotypes such as cancer. Phosphatase and tensin homologue deleted on chromosome ten (PTEN), one of the most commonly altered tumor suppressors in cancer, affects transcription via its role in antagonizing the PI3K/AK...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Steinbach, Nicole, Hasson, Dan, Mathur, Deepti, Stratikopoulos, Elias E, Sachidanandam, Ravi, Bernstein, Emily, Parsons, Ramon E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Gene regulation, Chromatin and Epigenetics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582409/
https://ncbi.nlm.nih.gov/pubmed/31169889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz272
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