DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute

Prokaryotic Argonaute proteins (pAgos) constitute a diverse group of endonucleases of which some mediate host defense by utilizing small interfering DNA guides (siDNA) to cleave complementary invading DNA. This activity can be repurposed for programmable DNA cleavage. However, currently characterize...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Hegge, Jorrit W, Swarts, Daan C, Chandradoss, Stanley D, Cui, Tao Ju, Kneppers, Jeroen, Jinek, Martin, Joo, Chirlmin, van der Oost, John
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582352/
https://ncbi.nlm.nih.gov/pubmed/31069393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz306
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