Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage

We report on crystal structures of ternary Thermus thermophilus Argonaute (TtAgo) complexes with 5′-phosphorylated guide DNA and a series of DNA targets. These ternary complex structures of cleavage-incompatible, cleavage-compatible, and postcleavage states solved at improved resolution up to 2.2 Å...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sheng, Gang, Zhao, Hongtu, Wang, Jiuyu, Rao, Yu, Tian, Wenwen, Swarts, Daan C., van der Oost, John, Patel, Dinshaw J., Wang, Yanli
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896195/
https://ncbi.nlm.nih.gov/pubmed/24374628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321032111
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados