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DNA sequence influences hexasome orientation to regulate DNA accessibility

Nucleosomes, the fundamental organizing units of eukaryotic genomes, contain ∼146 base pairs of DNA wrapped around a histone H3–H4 tetramer and two histone H2A–H2B dimers. Converting nucleosomes into hexasomes by removal of a H2A–H2B dimer is an important regulatory event, but its regulation and fun...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Brehove, Matthew, Shatoff, Elan, Donovan, Benjamin T, Jipa, Caroline M, Bundschuh, Ralf, Poirier, Michael G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582347/
https://ncbi.nlm.nih.gov/pubmed/31216039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz283
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