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Single nucleotide polymorphisms affect RNA-protein interactions at a distance through modulation of RNA secondary structures

Single nucleotide polymorphisms are widely associated with disease, but the ways in which they cause altered phenotypes are often unclear, especially when they appear in non-coding regions. One way in which non-coding polymorphisms could cause disease is by affecting crucial RNA-protein interactions...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Shatoff, Elan, Bundschuh, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237046/
https://ncbi.nlm.nih.gov/pubmed/32379750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007852
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