Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia

IMPORTANCE: A National Institute on Aging and Alzheimer’s Association workgroup proposed a research framework for Alzheimer disease in which biomarker classification of research participants is labeled AT(N) for amyloid, tau, and neurodegeneration biomarkers. OBJECTIVE: To determine the associations...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Jack, Clifford R., Wiste, Heather J., Therneau, Terry M., Weigand, Stephen D., Knopman, David S., Mielke, Michelle M., Lowe, Val J., Vemuri, Prashanthi, Machulda, Mary M., Schwarz, Christopher G., Gunter, Jeffrey L., Senjem, Matthew L., Graff-Radford, Jonathan, Jones, David T., Roberts, Rosebud O., Rocca, Walter A., Petersen, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582267/
https://ncbi.nlm.nih.gov/pubmed/31211344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.7437
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