Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia

IMPORTANCE: A National Institute on Aging and Alzheimer’s Association workgroup proposed a research framework for Alzheimer disease in which biomarker classification of research participants is labeled AT(N) for amyloid, tau, and neurodegeneration biomarkers. OBJECTIVE: To determine the associations...

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Dettagli Bibliografici
Pubblicato in:JAMA
Autori principali: Jack, Clifford R., Wiste, Heather J., Therneau, Terry M., Weigand, Stephen D., Knopman, David S., Mielke, Michelle M., Lowe, Val J., Vemuri, Prashanthi, Machulda, Mary M., Schwarz, Christopher G., Gunter, Jeffrey L., Senjem, Matthew L., Graff-Radford, Jonathan, Jones, David T., Roberts, Rosebud O., Rocca, Walter A., Petersen, Ronald C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2019
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582267/
https://ncbi.nlm.nih.gov/pubmed/31211344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.7437
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