Associations of Amyloid, Tau, and Neurodegeneration Biomarker Profiles With Rates of Memory Decline Among Individuals Without Dementia

IMPORTANCE: A National Institute on Aging and Alzheimer’s Association workgroup proposed a research framework for Alzheimer disease in which biomarker classification of research participants is labeled AT(N) for amyloid, tau, and neurodegeneration biomarkers. OBJECTIVE: To determine the associations...

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Vydáno v:JAMA
Hlavní autoři: Jack, Clifford R., Wiste, Heather J., Therneau, Terry M., Weigand, Stephen D., Knopman, David S., Mielke, Michelle M., Lowe, Val J., Vemuri, Prashanthi, Machulda, Mary M., Schwarz, Christopher G., Gunter, Jeffrey L., Senjem, Matthew L., Graff-Radford, Jonathan, Jones, David T., Roberts, Rosebud O., Rocca, Walter A., Petersen, Ronald C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2019
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582267/
https://ncbi.nlm.nih.gov/pubmed/31211344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.7437
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