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Rates of transition between amyloid and neurodegeneration biomarker states and to dementia among non-demented individuals: a population-based cohort study

BACKGROUND: We previously observed in a cross-sectional analysis that frequencies of amyloid and neurodegeneration biomarker states varied greatly by age among cognitively non-impaired participants, suggesting dynamic within-person processes. Our objective in this longitudinal study was to estimate...

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Detalhes bibliográficos
Publicado no:Lancet Neurol
Main Authors: Jack, Clifford R., Therneau, Terry M., Wiste, Heather J., Weigand, Stephen D., Knopman, David S., Lowe, Val J., Mielke, Michelle M., Vemuri, Prashanthi, Roberts, Rosebud O., Machulda, Mary M., Senjem, Matthew L., Gunter, Jeffrey L., Rocca, Walter A., Petersen, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784263/
https://ncbi.nlm.nih.gov/pubmed/26597325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(15)00323-3
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