Rates of transition between amyloid and neurodegeneration biomarker states and to dementia among non-demented individuals: a population-based cohort study

BACKGROUND: We previously observed in a cross-sectional analysis that frequencies of amyloid and neurodegeneration biomarker states varied greatly by age among cognitively non-impaired participants, suggesting dynamic within-person processes. Our objective in this longitudinal study was to estimate...

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Veröffentlicht in:Lancet Neurol
Hauptverfasser: Jack, Clifford R., Therneau, Terry M., Wiste, Heather J., Weigand, Stephen D., Knopman, David S., Lowe, Val J., Mielke, Michelle M., Vemuri, Prashanthi, Roberts, Rosebud O., Machulda, Mary M., Senjem, Matthew L., Gunter, Jeffrey L., Rocca, Walter A., Petersen, Ronald C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784263/
https://ncbi.nlm.nih.gov/pubmed/26597325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(15)00323-3
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