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Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies
Accurate prediction of drug-drug interactions (DDI) is a challenging task in drug discovery and development. It requires determination of enzyme inhibition in vitro which is highly system-dependent for many compounds. The aim of this study was to investigate whether the determination of intracellula...
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| Publicado no: | AAPS J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6581936/ https://ncbi.nlm.nih.gov/pubmed/31214810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-019-0344-8 |
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