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Synthesis of nucleoside analogs from hydrazine derivatives
Reaction of 6-hydrazino-l,3-dimethyluracil (1) with glycosyl isothiocyanates (2a,b,c) gave the glycosyl thiosemicarbazides (3a,b,c) in good yield, which were cyclized to pyrimidothiadiazines (5a,b,c) with NBS oxidation. And 5a,b,c were converted to pyrazolopyrimidines (6a,b,c) by thermal desulfuriza...
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| Gepubliceerd in: | Nucleic Acids Res |
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| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
1978
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6581323/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/1.suppl_2.s251 |
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