The CCCTC Binding Factor, CTRL2, Modulates Heterochromatin Deposition and the Establishment of Herpes Simplex Virus 1 Latency In Vivo

The cellular insulator protein CTCF plays a role in herpes simplex virus 1 (HSV-1) latency through the establishment and regulation of chromatin boundaries. We previously found that the CTRL2 regulatory element downstream from the latency-associated transcript (LAT) enhancer was bound by CTCF during...

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Vydáno v:J Virol
Hlavní autoři: Washington, Shannan D., Singh, Pankaj, Johns, Richard N., Edwards, Terri G., Mariani, Michael, Frietze, Seth, Bloom, David C., Neumann, Donna M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580944/
https://ncbi.nlm.nih.gov/pubmed/30996085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00415-19
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