Switchable CAR-T cells mediate remission in metastatic pancreatic ductal adenocarcinoma

OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is a disease of unmet medical need. While immunotherapy with chimeric antigen receptor T (CAR-T) cells has shown much promise in haematological malignancies, their efficacy for solid tumours is challenged by the lack of tumour-specific antigens requ...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Raj, Deepak, Yang, Ming-Hsin, Rodgers, David, Hampton, Eric N, Begum, Julfa, Mustafa, Arif, Lorizio, Daniela, Garces, Irene, Propper, David, Kench, James G, Kocher, H M, Young, Travis S, Aicher, Alexandra, Heeschen, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Pancreas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580747/
https://ncbi.nlm.nih.gov/pubmed/30121627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2018-316595
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