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Improving CAR T cell immunotherapy–mediated remissions for pediatric leukemia

Chimeric antigen receptor (CAR) T cells are an effective therapy for relapsed or refractory pediatric B cell leukemia. Analysis of the starting material, the T cells collected from the patient prior to CAR manufacture, reveals possible biomarkers of cells destined to perform poorly in patients. Long...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteur: Barrett, David M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486350/
https://ncbi.nlm.nih.gov/pubmed/30985293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128743
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