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Driving an improved CAR for cancer immunotherapy

The recent clinical success of chimeric antigen receptor (CAR) T cell therapy for B cell malignancies represents a paradigm shift in cancer immunotherapy. Unfortunately, application of CAR T cell–mediated therapy for solid tumors has so far been disappointing, and the reasons for this poor response...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Huang, Xiaopei, Yang, Yiping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966332/
https://ncbi.nlm.nih.gov/pubmed/27454296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88959
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