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Driving an improved CAR for cancer immunotherapy
The recent clinical success of chimeric antigen receptor (CAR) T cell therapy for B cell malignancies represents a paradigm shift in cancer immunotherapy. Unfortunately, application of CAR T cell–mediated therapy for solid tumors has so far been disappointing, and the reasons for this poor response...
Uloženo v:
Vydáno v: | J Clin Invest |
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Hlavní autoři: | , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
American Society for Clinical Investigation
2016
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966332/ https://ncbi.nlm.nih.gov/pubmed/27454296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88959 |
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