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Development of a Platform To Enable Efficient Permeability Evaluation of Novel Organo-Peptide Macrocycles
[Image: see text] As more macrocycle structures are utilized to drug intracellular targets, new platforms are needed to facilitate the discovery of cell permeable compounds in this unique chemical space. Herein, a method is disclosed that allows for the efficient synthesis and permeability evaluatio...
Gardado en:
| Publicado en: | ACS Med Chem Lett |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2019
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6580381/ https://ncbi.nlm.nih.gov/pubmed/31223441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00036 |
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