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Photoredox Ni-catalyzed peptide C(sp(2))–O cross-coupling: from intermolecular reactions to side chain-to-tail macrocyclization

Ni/photoredox (4DPAIPN) dual catalysis enabled challenging peptide C(sp(2))–O coupling reactions. Successful cross-coupling reactions were demonstrated with highly functionalized alcohols including side chains of amino acids (i.e., serine, threonine, tyrosine), trans-4-hydroxy-l-proline, alkyl alcoh...

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Vydáno v:Chem Sci
Hlavní autoři: Lee, Hyelee, Boyer, Nicolas C., Deng, Qiaolin, Kim, Hai-Young, Sawyer, Tomi K., Sciammetta, Nunzio
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524625/
https://ncbi.nlm.nih.gov/pubmed/31183058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00694j
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