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Designing Cell-Permeable Macrocyclic Peptides
Peptides provide an attractive modality for targeting challenging drug targets such as intracellular protein-protein interactions. Unfortunately, peptides are generally impermeable to the cell membrane and inherently susceptible to proteolytic degradation in vivo. Macrocyclization of peptides greatl...
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| Publié dans: | Methods Mol Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7277897/ https://ncbi.nlm.nih.gov/pubmed/31134566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9504-2_3 |
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