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Understanding Cell Penetration of Cyclic Peptides
Approximately 75% of all disease relevant human proteins including those involved in intracellular protein-protein interactions (PPIs) are undruggable with the current drug modalities (i.e., small molecules and biologics). Macrocyclic peptides provide a potential solution to these undruggable target...
Gardado en:
| Publicado en: | Chem Rev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6739158/ https://ncbi.nlm.nih.gov/pubmed/31083977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.9b00008 |
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