Assessment of pulsatile insulin secretion derived from peripheral plasma C-peptide concentrations by nonparametric stochastic deconvolution

The characteristics of pulsatile insulin secretion are important determinants of type 2 diabetes pathophysiology, but they are understudied due to the difficulties in measuring pulsatile insulin secretion noninvasively. Deconvolution of either peripheral C-peptide or insulin concentrations offers an...

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Bibliographic Details
Published in:Am J Physiol Endocrinol Metab
Main Authors: Laurenti, Marcello C., Vella, Adrian, Varghese, Ron T., Andrews, James C., Sharma, Anu, Kittah, Nana Esi, Rizza, Robert A., Matveyenko, Aleksey, De Nicolao, Giuseppe, Cobelli, Claudio, Dalla Man, Chiara
Format: Artigo
Language:Inglês
Published: American Physiological Society 2019
Subjects:
Innovative Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580177/
https://ncbi.nlm.nih.gov/pubmed/30807214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00519.2018
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