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Performance of individually-measured vs population-based C-peptide kinetics to assess β-cell function in presence and absence of acute insulin resistance

AIMS: Standardized, population-based kinetics of C-peptide distribution and clearance are used to estimate insulin secretion from plasma C-peptide concentrations without direct measurement of C-peptide kinetics. We then compared the performance of population-based kinetics to directly measured C-pep...

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Dettagli Bibliografici
Pubblicato in:Diabetes Obes Metab
Autori principali: Varghese, Ron T., Man, Chiara Dalla, Laurenti, Marcello C., Piccinini, Francesca, Sharma, Anu, Shah, Meera, Bailey, Kent R., Rizza, Robert A., Cobelli, Claudio, Vella, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946313/
https://ncbi.nlm.nih.gov/pubmed/28862812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13106
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