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Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle
Previous studies established that leucine stimulates protein synthesis in skeletal muscle to the same extent as a complete mixture of amino acids, and the effect occurs through activation of the mechanistic target of rapamycin in complex 1 (mTORC1). Recent studies using cells in culture showed that...
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| Publicado en: | Am J Physiol Endocrinol Metab |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Physiological Society
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6580170/ https://ncbi.nlm.nih.gov/pubmed/30835510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00522.2018 |
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