Telomere Maintenance-Associated PML Is a Potential Specific Therapeutic Target of Human Colorectal Cancer

Telomere length maintenance is essential for cell proliferation, which is particularly prominent in cancer. We validate that the primary colorectal tumors exhibit heterogeneous telomere lengths but mostly (90%) short telomeres relative to normal tissues. Intriguingly, relatively short telomeres are...

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Опубликовано в: :Transl Oncol
Главные авторы: Gong, Peng, Wang, Hua, Zhang, Jingsong, Fu, Yudong, Zhu, Zhengmao, Wang, Jinmiao, Yin, Yu, Wang, Haiying, Zhou, Zhongcheng, Yang, Jiao, Liu, Linlin, Gou, Mo, Zeng, Ming, Yuan, Jinghua, Wang, Feng, Pan, Xinghua, Xiang, Rong, Weissman, Sherman M., Qi, Feng, Liu, Lin
Формат: Artigo
Язык:Inglês
Опубликовано: Neoplasia Press 2019
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Original article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580093/
https://ncbi.nlm.nih.gov/pubmed/31207547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.05.010
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