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Feeders facilitate telomere maintenance and chromosomal stability of embryonic stem cells

Feeder cells like mouse embryonic fibroblasts (MEFs) have been widely applied for culture of pluripotent stem cells, but their roles remain elusive. Noticeably, ESCs cultured on the feeders display transcriptional heterogeneity. We investigated roles of feeder cells by examining the telomere mainten...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Guo, Renpeng, Ye, Xiaoying, Yang, Jiao, Zhou, Zhongcheng, Tian, Chenglei, Wang, Hua, Wang, Haiying, Fu, Haifeng, Liu, Chun, Zeng, Ming, Yang, Jun, Liu, Lin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6033898/
https://ncbi.nlm.nih.gov/pubmed/29976922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05038-2
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