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Feeders facilitate telomere maintenance and chromosomal stability of embryonic stem cells
Feeder cells like mouse embryonic fibroblasts (MEFs) have been widely applied for culture of pluripotent stem cells, but their roles remain elusive. Noticeably, ESCs cultured on the feeders display transcriptional heterogeneity. We investigated roles of feeder cells by examining the telomere mainten...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6033898/ https://ncbi.nlm.nih.gov/pubmed/29976922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05038-2 |
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