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Feeders facilitate telomere maintenance and chromosomal stability of embryonic stem cells
Feeder cells like mouse embryonic fibroblasts (MEFs) have been widely applied for culture of pluripotent stem cells, but their roles remain elusive. Noticeably, ESCs cultured on the feeders display transcriptional heterogeneity. We investigated roles of feeder cells by examining the telomere mainten...
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| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6033898/ https://ncbi.nlm.nih.gov/pubmed/29976922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05038-2 |
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