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DDAH1 regulates apoptosis and angiogenesis in human fetal pulmonary microvascular endothelial cells

Nitric Oxide (NO) is an endogenous pulmonary vasodilator produced by endothelial NO synthase (eNOS). Asymmetric dimethyl L‐arginine (ADMA) is an endogenous inhibitor of eNOS activity. In endothelial cells, ADMA is hydrolyzed to L‐citrulline primarily by dimethylarginine dimethyl‐aminohydrolase‐1 (DD...

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Bibliografiske detaljer
Udgivet i:Physiol Rep
Main Authors: Trittmann, Jennifer K., Almazroue, Hanadi, Jin, Yi, Nelin, Leif D.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579941/
https://ncbi.nlm.nih.gov/pubmed/31209995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14150
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