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An arginase‐1 SNP that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia enhances NO‐mediated apoptosis in lymphocytes
Arginase and nitric oxide synthase (NOS) share a common substrate, l‐arginine, and have opposing effects on vascular remodeling. Arginase is the first step in polyamine and proline synthesis necessary for cellular proliferation, while NO produced from NOS promotes apoptosis. Previously, we identifie...
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| Publicado no: | Physiol Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358007/ https://ncbi.nlm.nih.gov/pubmed/27895230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13041 |
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