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DDAH1 regulates apoptosis and angiogenesis in human fetal pulmonary microvascular endothelial cells

Nitric Oxide (NO) is an endogenous pulmonary vasodilator produced by endothelial NO synthase (eNOS). Asymmetric dimethyl L‐arginine (ADMA) is an endogenous inhibitor of eNOS activity. In endothelial cells, ADMA is hydrolyzed to L‐citrulline primarily by dimethylarginine dimethyl‐aminohydrolase‐1 (DD...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Trittmann, Jennifer K., Almazroue, Hanadi, Jin, Yi, Nelin, Leif D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579941/
https://ncbi.nlm.nih.gov/pubmed/31209995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14150
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