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Communication between distinct subunit interfaces of the cohesin complex promotes its topological entrapment of DNA

Cohesin mediates higher order chromosome structure. Its biological activities require topological entrapment of DNA within a lumen(s) formed by cohesin subunits. The reversible dissociation of cohesin’s Smc3p and Mcd1p subunits is postulated to form a regulated gate that allows DNA entry and exit in...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Guacci, Vincent, Chatterjee, Fiona, Robison, Brett, Koshland, Douglas E
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579514/
https://ncbi.nlm.nih.gov/pubmed/31162048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46347
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