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Communication between distinct subunit interfaces of the cohesin complex promotes its topological entrapment of DNA
Cohesin mediates higher order chromosome structure. Its biological activities require topological entrapment of DNA within a lumen(s) formed by cohesin subunits. The reversible dissociation of cohesin’s Smc3p and Mcd1p subunits is postulated to form a regulated gate that allows DNA entry and exit in...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579514/ https://ncbi.nlm.nih.gov/pubmed/31162048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46347 |
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