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Ribozyme-mediated, multiplex CRISPR gene editing and CRISPR interference (CRISPRi) in rodent-infectious Plasmodium yoelii

Malaria remains a major global health issue, affecting millions and killing hundreds of thousands of people annually. Efforts to break the transmission cycle of the causal Plasmodium parasite, and to cure those that are afflicted, rely upon functional characterization of genes essential to the paras...

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Pubblicato in:J Biol Chem
Autori principali: Walker, Michael P., Lindner, Scott E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579477/
https://ncbi.nlm.nih.gov/pubmed/31043479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007121
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